|Title||Saliva cortisol and exposure to aircraft noise in six European countries.|
|Publication Type||Journal Article|
|Year of Publication||2009|
|Authors||Selander J, Bluhm G, Theorell T, Pershagen G, Babisch W, Seiffert I, Houthuijs D, Breugelmans O, Vigna-Taglianti F, Antoniotti M C, Velonakis E, Davou E, Dudley M-L, Järup L|
|Corporate Authors||HYENA Consortium|
|Journal||Environ Health Perspect|
|Date Published||2009 Nov|
|Keywords||Aged, Aircraft, Cardiovascular Diseases, Cross-Sectional Studies, Environmental Exposure, Europe, Female, Humans, Hydrocortisone, Male, Middle Aged, Noise, Transportation, Saliva, Sex Factors, Time Factors|
BACKGROUND: Several studies show an association between exposure to aircraft or road traffic noise and cardiovascular effects, which may be mediated by a noise-induced release of stress hormones.
OBJECTIVE: Our objective was to assess saliva cortisol concentration in relation to exposure to aircraft noise.
METHOD: A multicenter cross-sectional study, HYENA (Hypertension and Exposure to Noise near Airports), comprising 4,861 persons was carried out in six European countries. In a subgroup of 439 study participants, selected to enhance the contrast in exposure to aircraft noise, saliva cortisol was assessed three times (morning, lunch, and evening) during 1 day.
RESULTS: We observed an elevation of 6.07 nmol/L [95% confidence interval (CI), 2.32-9.81 nmol/L] in morning saliva cortisol level in women exposed to aircraft noise at an average 24-hr sound level (L(Aeq,24h)) > 60 dB, compared with women exposed to L(Aeq,24h) < or = 50 dB, corresponding to an increase of 34%. Employment status appeared to modify the response. We found no association between noise exposure and saliva cortisol levels in men.
CONCLUSIONS: Our results suggest that exposure to aircraft noise increases morning saliva cortisol levels in women, which could be of relevance for noise-related cardiovascular effects.
|Alternate Journal||Environ. Health Perspect.|